Xovoltib 40 Mg is a pharmaceutical drug used for the treatment of advanced stages of NSCLC (non-small cell lung cancer) in combination with other drugs. Afatinib Dimaleate is related to a class of drugs called Tyrosine Kinase Inhibitors (TKIs). One of the mechanisms of action of TKIs is binding to and inhibiting the function of specific receptors called tyrosine kinases. This leads to the inhibition of signal transduction pathways that are involved in cell growth, proliferation and differentiation.
Xovoltib 40 Mg may be prescribed for adults with metastatic NSCLC that has certain EGFR gene mutations. Before treatment, doctors generally recommend appropriate diagnostic testing to determine whether the cancer has mutations that may respond to afatinib. It can also be used in specific cases of metastatic squamous NSCLC following progression after platinum-based chemotherapy.
How to Take Xovoltib 40 Mg?
The usual starting dose of afatinib for many patients is 40 mg once daily, but the dosage may be adjusted by the treating doctor depending on tolerability and individual medical circumstances. It is generally taken on an empty stomach, at least one hour before or two hours after eating. The tablet should be taken exactly as prescribed and should not be stopped or changed without medical advice.
Side Effects and Precautions
Common side effects may include diarrhea, skin rash, dry skin, mouth sores, decreased appetite, and nail changes. Some side effects can become serious, so persistent diarrhea, severe skin reactions, breathing difficulties, eye problems, or other unusual symptoms should be reported to a healthcare professional promptly.
Xovoltib 40 Mg is a prescription medicine and should be used only under the supervision of a qualified oncologist. Patients should inform their doctor about existing medical conditions and all medicines or supplements they are taking before starting treatment.
| Composition | Afatinib dimaleate (40mg) |
|---|---|
| Dosage Form | Tablets |
| Equivalent Brand | Gilotrif |
| Generic Name | Afatinib dimaleate |
| Indication | Used to treat non-small cell lung carcinoma (NSCLC) |
| Manufacturer | Boehringer Ingelheim |
| Packaging | Strip of 7 Tablets |
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